SCHEMBL3898461

SCHEMBL3898461

C[C@@H](O)[C@H](N)C(=O)OC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.38
NPY1R P25929 6/20 0.38
NPY2R P49146 4/20 0.36
NPY5R Q15761 4/20 0.36
DPP7 Q9UHL4 2/20 0.35
OTC P00480 1/20 0.32
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
ANPEP P15144 2/20 0.31
RNPEP Q9H4A4 2/20 0.31
ALOX15 P16050 1/20 0.31
DNPEP Q9ULA0 1/20 0.31
DDAH1 O94760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27926299 0.90 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL4586463 0.90 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL323016 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL30531669 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL15653883 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
Threonine SCHEMBL285577 0.89 NPY4R (0.36) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL9237239 0.88 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL288133 0.88 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL28712062 0.88 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL1821005 0.87 NPY4R (0.40) NPY4RNPY1RNPY2RNPY5RDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102220299-A Feruloyl esterase A mutant and application thereof CHENGDU INST BIOLOGY CAS 2011-10-19 CN claimed
US-10633422-B2 Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF) (US) 2020-04-28 US disclosed
US-20160355790-A1 INFLUENZA VIRUS REPLICATION BY INHIBITING MICRORNA LEC7C BINDING TO INFLUENZA VIRAL CRNA AND MRNA NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-12-08 US disclosed
US-7544469-B2 Methods and compositions for optical detection of single-stranded polynucleotides THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2009-06-09 US disclosed
US-20090011404-A9 Methods and compositions for optical detection of single-stranded polynucleotides UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2009-01-08 US disclosed
US-20070178455-A1 Methods and compositions for optical detection of single-stranded polynucleotides UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2007-08-02 US disclosed