Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3900462 | 0.88 | ADRA2A (0.43) | F10ADRA2AADRA2BADRA2CPTGIR | |
| Trifluoroacetic Acid SCHEMBL3898866 | 0.87 | F10 (0.62) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3905955 | 0.85 | F10 (0.67) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3895029 | 0.83 | F10 (0.86) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3898231 | 0.82 | F10 (0.60) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3909154 | 0.81 | F10 (0.72) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3903060 | 0.81 | F10 (0.79) | F10PRSS1PRSS2PRSS3KLK1 | |
| SCHEMBL14132002 | 0.81 | F10 (0.69) | F10PRSS1KLK1PLGPROC | |
| Trifluoroacetic Acid SCHEMBL3903054 | 0.80 | F10 (0.77) | F10PRSS1PRSS2PRSS3KLK1 | |
| Trifluoroacetic Acid SCHEMBL3911547 | 0.80 | F10 (0.77) | F10PRSS1PRSS2PRSS3KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |