SCHEMBL3898720

SCHEMBL3898720

COc1cccc(C[SiH3])c1OC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
ABCB1 P08183 3/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
ABCG2 Q9UNQ0 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA14 Q9ULX7 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
TSHR P16473 1/20 0.49
CRHBP P24387 1/20 0.49
MAPK1 P28482 1/20 0.49
CRHR2 Q13324 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306584 0.83 SMN1; SMN2 (0.54) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL464374 0.81 CA12 (0.54) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL27708944 0.80 SMN1; SMN2 (0.56) SMN1; SMN2ABCB1KDM4EALDH1A1CA12
SCHEMBL29740292 0.80 CA1 (0.62) SMN1; SMN2KDM4EALDH1A1CA12CA1
SCHEMBL400747 0.79 IDO1 (0.50) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
Ammonia Solution, Strong SCHEMBL7313508 0.79 CA12 (0.53) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL216572 0.79 SMN1; SMN2 (0.50) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL17420764 0.79 SMN1; SMN2 (0.50) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL95872 0.79 CA12 (0.53) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2
SCHEMBL4369269 0.79 ABCB1 (0.57) SMN1; SMN2ABCB1KDM4EALDH1A1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015592-B1 CURABLE CONDENSATION COMPOUNDS ON THE BASIS OF ALKOXY-FUNCTIONAL POLYSILOXANES EVONIK OPERATIONS GMBH (DE) 2026-03-18 EP claimed
US-12460081-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2025-11-04 US claimed
US-12152109-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2024-11-26 US claimed
EP-4186954-A1 CURABLE CONDENSATION COMPOUNDS BASED ON ALKOXY-FUNCTIONAL POLYSILOXANES Evonik Operations GmbH (DE) 2023-05-31 EP claimed
CN-116162247-A Curable condensation compounds based on alkoxy-functional polysiloxanes 赢创运营有限公司 2023-05-26 CN claimed
US-20230159756-A1 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2023-05-25 US claimed
CN-114621445-A Curable condensation compounds based on alkoxy-functional polysiloxanes 赢创运营有限公司 2022-06-14 CN claimed
US-20220177652-A1 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2022-06-09 US claimed
CN-110218382-B Antenna housing material 西安安聚德纳米科技有限公司 2022-03-11 CN claimed
US-12460081-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2025-11-04 US disclosed
US-12152109-B2 Curable condensation compounds based on alkoxy-functional polysiloxanes EVONIK OPERATIONS GMBH (DE) 2024-11-26 US disclosed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US disclosed
WO-2024096021-A1 HYDROPHOBIC LOW-LOSS-TANGENT SILICA SOL AND PRODUCTION METHOD THEREFOR 日産化学株式会社 2024-05-10 WO disclosed
EP-3036296-B1 COATING COMPOUNDS EVONIK OPERATIONS GMBH (DE) 2023-07-12 EP disclosed
WO-2003040200-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
WO-2003040193-A2 METHOD FOR POLYMERIZING LENSES BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
WO-2003040214-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED PREPOLYMER PRECURSORS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
US-5378788-A Process for preparation of linear organo-polysiloxane having hydroxyl group at its molecular ends SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-01-03 US disclosed
US-4717770-A CYCLOHEXANONE OXIME, ZEOLITES, SURFACE TREATMENT WITH ORGANOSILICON OR ORGANOGERMANIUM COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 1988-01-05 US disclosed
EP-0236092-A2 Process for producing e-caprolactam SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 SMN1; SMN2 3310/4885ABCB1 4525/4885KDM4E 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.