Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
| ▸ | NEK4 | P51957 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19190687 | 0.86 | RAB9A (0.52) | CLK4HDAC1ABCB1ABCG2KDM4E | |
| SCHEMBL12312888 | 0.86 | MAP3K8 (0.46) | PTPN1PTPN11ROCK2MAP4K4PRKCG | |
| SCHEMBL3900134 | 0.85 | ABCG2 (0.48) | ROCK2MAP4K4PRKCGLYNPRKACA | |
| SCHEMBL2868935 | 0.81 | PTPN1 (0.55) | PTPN1PTPN11ROCK2MAP4K4PRKCG | |
| SCHEMBL1455414 | 0.80 | APP (0.43) | CSNK1DDYRK1AKDM4EGAAKMT2A | |
| SCHEMBL22585064 | 0.80 | NPC1 (0.48) | CSNK1DHDAC1ABCB1ABCG2KDM4E | |
| SCHEMBL3902789 | 0.80 | NPC1 (0.48) | CSNK1DHDAC1ABCB1ABCG2KDM4E | |
| SCHEMBL20485970 | 0.78 | CA1 (0.45) | DYRK1AKDM4EGAAPOLBKMT2A | |
| SCHEMBL15927533 | 0.77 | GAA (0.45) | CSNK1DDYRK1ADHFRKDM4EGAA | |
| SCHEMBL18266775 | 0.76 | CHEK1 (0.37) | CSNK1DKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524876-B2 | Luciferase substrate; non-luminescent, but changes to a luminescent substrate due to molecular structural alteration in the presence of a target molecule; alkylation of amino group shifted emission to longer wavelength; useful for in vivo imaging | THE UNIVERSITY OF TOKYO (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20070155806-A1 | Novel luciferin derivatives | THE UNIVERSITY OF TOKYO (JP) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155806-A1 | Novel luciferin derivatives | GLB1, LUC7L2, RXFP1 | PTPN1 4221/4885PTPN11 4366/4885ROCK2 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.