Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 14/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902703 | 0.92 | NR1H2 (0.52) | ERN1CDK1TRIM24TRIM33ESR2 | |
| SCHEMBL7542850 | 0.91 | BCL2 (0.50) | ERN1CDK1TRIM24TRIM33 | |
| SCHEMBL16584979 | 0.85 | MAOA (0.47) | ERN1CDK1ESR2 | |
| SCHEMBL2641952 | 0.83 | ERN1 (0.52) | ERN1CDK1TRIM24TRIM33 | |
| SCHEMBL6094668 | 0.83 | ERN1 (0.57) | ERN1CDK1TRIM24TRIM33ESR2 | |
| SCHEMBL11114793 | 0.82 | ERN1 (0.58) | ERN1TRIM24TRIM33 | |
| SCHEMBL11214988 | 0.79 | CDK1 (0.57) | CDK1 | |
| SCHEMBL16555488 | 0.79 | ERN1 (0.47) | ERN1CDK1TRIM24TRIM33 | |
| SCHEMBL10916030 | 0.79 | ERN1 (0.47) | ERN1CDK1TRIM24TRIM33 | |
| SCHEMBL6206480 | 0.77 | ERN1 (0.57) | ERN1CDK1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072002-A2 | BISPHENOLS IN CANCER THERAPY | UNIVERSITY OF MANITOBA (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009072002-A2 | BISPHENOLS IN CANCER THERAPY | UNIVERSITY OF MANITOBA (US) | 2009-06-11 | — | — | WO | disclosed |