Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 16/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899644 | 0.82 | ERN1 (0.55) | ERN1TRIM24TRIM33 | |
| SCHEMBL7542850 | 0.81 | BCL2 (0.50) | ERN1TRIM24TRIM33 | |
| SCHEMBL3902703 | 0.76 | NR1H2 (0.52) | ERN1TRIM24TRIM33 | |
| SCHEMBL6644954 | 0.74 | ERN1 (1.00) | ERN1 | |
| SCHEMBL29396037 | 0.74 | ERN1 (1.00) | ERN1 | |
| SCHEMBL9548473 | 0.73 | CYP2A6 (0.50) | KDM4E | |
| SCHEMBL11111047 | 0.72 | NR1H2 (0.56) | KDM4ERAB9AKMT2A | |
| SCHEMBL6166029 | 0.71 | ERN1 (0.58) | ERN1 | |
| SCHEMBL11111298 | 0.71 | ERN1 (0.58) | ERN1 | |
| SCHEMBL16584979 | 0.70 | MAOA (0.47) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455427-A | THROMBOXANE INHIBITORS | THE UPJOHN COMPANY (US) | 1984-06-19 | — | — | US | disclosed |
| EP-0069521-A2 | Pyridinyl and imidazolyl derivatives of benzofurans and benzothiophenes | THE UPJOHN COMPANY (US) | 1983-01-12 | — | — | EP | disclosed |