Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.53 |
| ▸ | F2 | P00734 | 9/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.51 |
| ▸ | KLK1 | P06870 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132064 | 0.92 | F10 (0.58) | F10F2PRSS1PLAT | |
| Trifluoroacetic Acid SCHEMBL6637824 | 0.76 | F10 (0.88) | F10F2PRSS1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL7900413 | 0.74 | F10 (0.71) | F10F2PRSS1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL3895029 | 0.74 | F10 (0.86) | F10F2PRSS1KLK1 | |
| Trifluoroacetic Acid SCHEMBL3896482 | 0.74 | F10 (0.76) | F10F2PRSS1TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL6643271 | 0.74 | F10 (0.73) | F10F2PRSS1KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL3896058 | 0.73 | F10 (0.57) | F10F2KLK1KLK5TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL3900211 | 0.73 | F10 (0.80) | F10F2PRSS1KLK1 | |
| SCHEMBL9542310 | 0.73 | NPC1 (0.56) | F10 | |
| SCHEMBL9790512 | 0.73 | NPC1 (0.56) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |