Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790512 | 1.00 | NPC1 (0.56) | NPC1RAB9AMAOBGAALMNA | |
| SCHEMBL7322092 | 0.92 | HDAC1 (0.67) | NPC1RAB9AMAOBLMNAALDH1A1 | |
| SCHEMBL7315952 | 0.92 | HDAC1 (0.67) | NPC1RAB9AMAOBLMNAALDH1A1 | |
| SCHEMBL7316237 | 0.92 | HDAC1 (0.53) | NPC1RAB9AMAOBGAALMNA | |
| SCHEMBL7319093 | 0.92 | HDAC1 (0.53) | NPC1RAB9AMAOBGAALMNA | |
| SCHEMBL7316244 | 0.92 | HDAC1 (0.53) | NPC1RAB9AMAOBGAALMNA | |
| SCHEMBL7315942 | 0.92 | HDAC1 (0.67) | NPC1RAB9AMAOBLMNAALDH1A1 | |
| SCHEMBL9790455 | 0.89 | LMNA (0.56) | NPC1RAB9AMAOBLMNAALDH1A1 | |
| SCHEMBL9790511 | 0.89 | LMNA (0.59) | NPC1RAB9AMAOBGAALMNA | |
| SCHEMBL9790510 | 0.89 | RAB9A (0.51) | NPC1RAB9AMAOBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105408-B | Novel asymmetric catalytic nucleophilic fluorine heterocyclic reaction system and application thereof in chiral unnatural amino acid module synthesis | 深圳市图微安创科技开发有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-118373763-A | Allylamine compound and preparation method thereof | 华中师范大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-113105408-B | Novel asymmetric catalytic nucleophilic fluorine heterocyclic reaction system and application thereof in chiral unnatural amino acid module synthesis | 深圳市图微安创科技开发有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |
| US-4994569-A | Cholecystokinin antagonists | RHONE-POULENC SANTE (FR) | 1991-02-19 | — | — | US | disclosed |
| US-4957533-A | THIOAMIDES, AMIDINES | ELI LILLY AND COMPANY (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0314422-A2 | N-phenylalkylbenzamide fungicides | DOWELANCO (US) | 1989-05-03 | — | — | EP | disclosed |