Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 10/20 | 0.46 |
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898190 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1GPR34PPARG | |
| SCHEMBL3900080 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1GPR34PPARG | |
| SCHEMBL17492189 | 0.89 | PTPN1 (0.49) | ITGB3ITGA2BPTPN1GPR34PPARG | |
| SCHEMBL17492191 | 0.89 | PTPN1 (0.49) | ITGB3ITGA2BPTPN1GPR34PPARG | |
| SCHEMBL11370281 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1PPARGCTSS | |
| SCHEMBL9089276 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1PPARGCTSS | |
| SCHEMBL9089268 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1PPARGCTSS | |
| SCHEMBL9089274 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1PPARGCTSS | |
| SCHEMBL11457050 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BPTPN1PPARGCTSS | |
| SCHEMBL1336085 | 0.83 | CTSS (0.61) | PTPN1PPARGCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |