Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895709 | 1.00 | F10 (0.47) | F10AAK1PIN1CTSSCTSK | |
| SCHEMBL3911676 | 0.90 | AAK1 (0.44) | AAK1CTSSCTSKGPR34HDAC3 | |
| SCHEMBL3909952 | 0.90 | AAK1 (0.44) | AAK1CTSSCTSKGPR34HDAC3 | |
| SCHEMBL3900359 | 0.88 | ATM (0.53) | CTSSCTSKGPR34HDAC3HDAC4 | |
| SCHEMBL17492189 | 0.85 | PTPN1 (0.49) | CTSSCTSKGPR34CTSBCTSL | |
| SCHEMBL17492191 | 0.85 | PTPN1 (0.49) | CTSSCTSKGPR34CTSBCTSL | |
| SCHEMBL18428084 | 0.84 | F10 (0.49) | F10AAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL28517888 | 0.84 | F10 (0.49) | F10AAK1HDAC3HDAC4HDAC1 | |
| SCHEMBL17492210 | 0.82 | CTSS (0.44) | CTSSCTSKGPR34CTSBCTSL | |
| SCHEMBL17492209 | 0.82 | CTSS (0.44) | CTSSCTSKGPR34CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |