Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 9/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639552 | 0.88 | ATM (0.65) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL3900532 | 0.88 | F10 (0.47) | CTSSCTSKCTSBCTSLGPR34 | |
| SCHEMBL3895709 | 0.88 | F10 (0.47) | CTSSCTSKCTSBCTSLGPR34 | |
| SCHEMBL6164289 | 0.86 | CTSS (0.45) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL3904538 | 0.86 | GPR34 (0.57) | GPR34SMN1; SMN2 | |
| SCHEMBL3909952 | 0.86 | AAK1 (0.44) | CTSSCTSKCTSBGPR34SMN1; SMN2 | |
| SCHEMBL3911676 | 0.86 | AAK1 (0.44) | CTSSCTSKCTSBGPR34SMN1; SMN2 | |
| SCHEMBL6854832 | 0.84 | ATM (0.56) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL17492189 | 0.83 | PTPN1 (0.49) | CTSSCTSKCTSBCTSLGPR34 | |
| SCHEMBL17492191 | 0.83 | PTPN1 (0.49) | CTSSCTSKCTSBCTSLGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |