Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811614 | 0.94 | MAOB (0.64) | MAOBAS3MTAPPFFAR1FFAR4 | |
| SCHEMBL27510264 | 0.86 | MAOB (0.53) | MAOBAPPFFAR1FFAR4MAOA | |
| SCHEMBL22874523 | 0.84 | MAOB (0.62) | MAOBFFAR1FFAR4MAOAMRGPRX4 | |
| SCHEMBL538272 | 0.84 | MAOB (0.69) | MAOBFFAR1FFAR4MAOAGPR34 | |
| SCHEMBL30344886 | 0.84 | MAOB (0.69) | MAOBFFAR1FFAR4MAOAGPR34 | |
| SCHEMBL7452913 | 0.83 | GABRG2 (0.56) | MAOBFFAR1FFAR4MAOAMRGPRX4 | |
| SCHEMBL8509859 | 0.83 | FFAR1 (0.56) | MAOBFFAR1FFAR4MAOAMRGPRX4 | |
| SCHEMBL810451 | 0.83 | MAOB (0.66) | MAOBAS3MTAPPMAOAF2 | |
| SCHEMBL1248693 | 0.82 | MAOB (0.66) | MAOBFFAR1FFAR4MAOAMRGPRX4 | |
| SCHEMBL31114416 | 0.82 | MAOB (0.79) | MAOBAPPMAOACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |