Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900673 | 0.89 | HSD11B1 (0.52) | HSD11B1CYP2D6 | |
| SCHEMBL350029 | 0.84 | HSD11B1 (0.51) | HSD11B1CYP2D6 | |
| SCHEMBL350776 | 0.83 | HSD11B1 (0.53) | HSD11B1CYP2D6 | |
| SCHEMBL349076 | 0.78 | HSD11B1 (0.61) | HSD11B1CYP2D6 | |
| SCHEMBL350014 | 0.75 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL349846 | 0.74 | HSD11B1 (0.78) | HSD11B1CYP2D6 | |
| SCHEMBL7176061 | 0.72 | DRD2 (0.52) | HSD11B1 | |
| SCHEMBL349790 | 0.72 | HSD11B1 (0.71) | HSD11B1CYP2D6 | |
| SCHEMBL349352 | 0.71 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL351003 | 0.71 | HSD11B1 (0.59) | HSD11B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |