Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | WDR5 | P61964 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
| ▸ | NPY1R | P25929 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | FASN | P49327 | 2/20 | 0.56 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dexrabeprazole SCHEMBL22189141 | 0.86 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL491358 | 0.86 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL2998947 | 0.86 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL140495 | 0.86 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL2998946 | 0.86 | KMT2A (0.60) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL27964348 | 0.85 | KMT2A (0.59) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Dexrabeprazole SCHEMBL4946138 | 0.84 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL29374701 | 0.84 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL29360086 | 0.84 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAALDH1A1 | |
| Rabeprazole SCHEMBL23337 | 0.84 | KMT2A (0.61) | KMT2ACYP2C9WDR5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137633-A1 | Stable pharmaceutical composition of rabeprazole | CADILA PHARMACEUTICALS LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| EP-1660083-A4 | STABLE PHARMACEUTICAL COMPOSITION OF RABEPRAZOLE | CADILA PHARMACEUTICALS LTD (IN) | 2009-03-25 | — | — | EP | disclosed |
| EP-1660083-A2 | STABLE PHARMACEUTICAL COMPOSITION OF RABEPRAZOLE | Khamar, Bakulesh Mafatlal (IN) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016225-A2 | STABLE PHARMACEUTICAL COMPOSITION OF RABEPRAZOLE | KHAMAR BAKULESH MAFATLAL (IN) | 2005-02-24 | — | — | WO | disclosed |