Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | MLNR | O43193 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | GHSR | Q92847 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910855 | 0.87 | MAOA (0.52) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL31128388 | 0.79 | DRD3 (1.00) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL25946 | 0.79 | DRD3 (1.00) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL2258789 | 0.78 | DRD3 (0.98) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL1649725 | 0.77 | DRD3 (0.96) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL28086487 | 0.74 | DRD3 (0.89) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| SCHEMBL982499 | 0.74 | MAPK1 (0.75) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| Caroverine SCHEMBL7279211 | 0.73 | DRD3 (0.85) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| SCHEMBL3881842 | 0.72 | MLNR (0.62) | PDE4DMLNRADORA3ADRA2BADRA2C | |
| SCHEMBL979729 | 0.72 | MAPK1 (0.68) | PDE4DMLNRADORA3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530455-B1 | A PHARMACEUTICAL FORMULATION AND ITS USE IN THE TREATMENT OF INNER EAR DISEASES | PHAFAG AG (LI) | 2009-03-18 | — | — | EP | claimed |