Caroverine

Caroverine

SCHEMBL25946

CCN(CC)CCn1c(=O)c(Cc2ccc(OC)cc2)nc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 1.00
MLNR O43193 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
HTR2A P28223 1/20 1.00
HTR2C P28335 1/20 1.00
ADRA1A P35348 1/20 1.00
PTGS2 P35354 1/20 1.00
HRH1 P35367 1/20 1.00
OPRD1 P41143 1/20 1.00
OPRK1 P41145 1/20 1.00
HTR3A P46098 1/20 1.00
PDE4D Q08499 1/20 1.00
KCNH2 Q12809 1/20 1.00
GHSR Q92847 1/20 1.00
HRH3 Q9Y5N1 1/20 1.00
TSPO P30536 1/20 0.52
CNR2 P34972 2/20 0.52
PKM P14618 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caroverine SCHEMBL31128388 1.00 DRD3 (1.00) DRD3MLNRADORA3ADRA2BADRA2C
Caroverine SCHEMBL2258789 0.99 DRD3 (0.98) DRD3MLNRADORA3ADRA2BADRA2C
Caroverine SCHEMBL1649725 0.98 DRD3 (0.96) DRD3MLNRADORA3ADRA2BADRA2C
Caroverine SCHEMBL28086487 0.94 DRD3 (0.89) DRD3MLNRADORA3ADRA2BADRA2C
Caroverine SCHEMBL7279211 0.92 DRD3 (0.85) DRD3MLNRADORA3ADRA2BADRA2C
Caroverine SCHEMBL11330670 0.87 DRD3 (0.76) DRD3MLNRADORA3ADRA2BADRA2C
SCHEMBL3881848 0.87 MLNR (0.77) DRD3MLNRADORA3ADRA2BADRA2C
SCHEMBL3900890 0.79 PDE4D (0.65) DRD3MLNRADORA3ADRA2BADRA2C
SCHEMBL3881842 0.77 MLNR (0.62) DRD3MLNRADORA3ADRA2BADRA2C
SCHEMBL982499 0.74 MAPK1 (0.75) DRD3MLNRADORA3ADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250152568-A1 METHODS OF TREATING COMPLEX REGIONAL PAIN SYNDROME AISA PHARMA, INC. 2025-05-15 US claimed
EP-4475887-A1 METHODS OF TREATING COMPLEX REGIONAL PAIN SYNDROME Aisa Pharma, Inc. (US) 2024-12-18 EP claimed
WO-2024211216-A1 CILNIDIPINE AND A P-GLYCOPROTEIN INHIBITOR FOR TREATING PAIN AISA PHARMA, INC. (US) 2024-10-10 WO claimed
WO-2023150336-A1 METHODS OF TREATING COMPLEX REGIONAL PAIN SYNDROME AISA PHARMA, INC. (US) 2023-08-10 WO claimed
US-11065205-B2 Immediate/delayed drug delivery DRUG DELIVERY INTERNATIONAL LIMITED (GB) 2021-07-20 US claimed
US-10695168-B2 Prosthetic devices for semicircular canal defects MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2020-06-30 US claimed
US-20190125679-A1 IMMEDIATE/DELAYED DRUG DELIVERY UNIVERSITY OF STRATHCLYDE (GB) 2019-05-02 US claimed
EP-3373943-A1 CONTROL OF CELLULAR REDOX LEVELS Mckenna, Elizabeth (US) 2018-09-19 EP claimed
CN-108430482-A Control of cellular redox levels 伊丽莎白·麦克纳 2018-08-21 CN claimed
EP-2956450-B1 HYDROXYINDALPINE DERIVATIVES AND THEIR MEDICAL USE UNIV MUENCHEN TECH (DE) 2018-07-25 EP claimed
US-20050288292-A1 Pharmaceutical formulation and its use in the treatment of inner ear diseases PHAFAG AG (LI) 2005-12-29 US claimed
CN-1379686-A Composition comprising tramadol material and anticonvulsant drug ORTHO MCNEIL PHARM INC (US) 2002-11-13 CN claimed
US-20010006966-A1 Use of 1- (aminoalkyl) -3-quinoxaline-2-on derivatives for the preparation of compounds having an antioxidant action PHAFAG AKTIENGESELLSCHAFT (LI) 2001-07-05 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-0542689-B1 Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions PHAFAG AG (LI) 1998-09-23 EP claimed
US-5563140-A Use of 1-(aminoalkyl)-3-(benzyl)-quinoxaline-2-one derivatives for the preparation of neuroprotective compositions PHAFAG AKTIENGESELLSCHAFT (LI) 1996-10-08 US claimed
EP-0639986-A1 TOPICAL OPHTHALMIC COMPOSITIONS COMPRISING A COMBINATION OF CALCIUM ANTAGONISTS WITH KNOWN ANTIGLAUCOMA AGENTS ALCON LABORATORIES, INC. (US) 1995-03-01 EP claimed
WO-1993023082-A1 TOPICAL OPHTHALMIC COMPOSITIONS COMPRISING A COMBINATION OF CALCIUM ANTAGONISTS WITH KNOWN ANTIGLAUCOMA AGENTS ALCON LABORATORIES, INC. (US) 1993-11-25 WO claimed
EP-0542689-A1 Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions PHAFAG AKTIENGESELLSCHAFT (LI) 1993-05-19 EP claimed
WO-1992016226-A1 IL-1 INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1992-10-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006966-A1 Use of 1- (aminoalkyl) -3-quinoxaline-2-on derivatives for the preparation of compounds having an antioxidant action GLS, GLUL, GLS2 DRD3 928/4885MLNR 1977/4885ADORA3 705/4885
US-20050288292-A1 Pharmaceutical formulation and its use in the treatment of inner ear diseases SLC26A4, TIMM10, AQP1 DRD3 3212/4885MLNR 3939/4885ADORA3 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.