Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381016 | 0.85 | TAAR1 (0.56) | CYP19A1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL4196224 | 0.85 | CFTR (0.57) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3910832 | 0.81 | TAAR1 (0.64) | CYP19A1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL5307787 | 0.81 | HTR2A (0.64) | CFTRSLC6A2SLC6A4SLC6A3GOPC | |
| SCHEMBL3911314 | 0.76 | HTR2A (0.45) | CYP19A1HTR2ATAAR1 | |
| SCHEMBL20773646 | 0.75 | CTSA (0.47) | CYP19A1CTSA | |
| SCHEMBL1034162 | 0.74 | HTR2A (0.68) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3904458 | 0.74 | SLC6A2 (0.47) | CYP19A1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL3282177 | 0.73 | NOS1 (0.44) | SLC6A2SLC6A4SLC6A3LMNAKCNH2 | |
| SCHEMBL3903975 | 0.72 | CYP11B1 (0.44) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |