Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25219221 | 0.85 | SLC6A2 (0.47) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL27511961 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL1422822 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL2066147 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL31214343 | 0.82 | SLC6A2 (0.44) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7927468 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL16702791 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7864529 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL6996545 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL7001280 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4CHRM2SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |