Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314368 | 0.91 | TBXAS1 (0.52) | TBXAS1GSK3BHRH1CCR3SMN1; SMN2 | |
| SCHEMBL4948901 | 0.90 | TBXAS1 (0.51) | TBXAS1GSK3BHRH1CCR3FFAR1 | |
| SCHEMBL22120309 | 0.88 | TBXAS1 (0.50) | TBXAS1GSK3BFFAR1 | |
| SCHEMBL30826996 | 0.88 | TBXAS1 (0.50) | TBXAS1GSK3BFFAR1 | |
| SCHEMBL11033727 | 0.88 | TBXAS1 (0.50) | TBXAS1GSK3BFFAR1 | |
| SCHEMBL27969567 | 0.85 | TBXAS1 (0.49) | TBXAS1GSK3BSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL7388461 | 0.85 | TBXAS1 (0.56) | TBXAS1HRH1CCR3 | |
| SCHEMBL13684905 | 0.84 | TBXAS1 (0.55) | TBXAS1GSK3BHRH1CCR3SMN1; SMN2 | |
| SCHEMBL20552139 | 0.84 | TBXAS1 (0.55) | TBXAS1HRH1CCR3SMN1; SMN2SLC6A2 | |
| SCHEMBL687723 | 0.82 | TBXAS1 (0.54) | TBXAS1HRH1CCR3SMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |