Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901457 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PKMERCC5FEN1 | |
| SCHEMBL1426693 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2PKMC3AR1RAB9A | |
| SCHEMBL8985344 | 0.82 | ERCC5 (0.44) | ALDH1A1SMN1; SMN2PKMERCC5FEN1 | |
| SCHEMBL28272575 | 0.82 | ERCC5 (0.44) | ALDH1A1SMN1; SMN2PKMERCC5FEN1 | |
| SCHEMBL9956081 | 0.80 | C3AR1 (0.40) | ALDH1A1SMN1; SMN2PKMC3AR1L3MBTL1 | |
| SCHEMBL9956085 | 0.80 | C3AR1 (0.40) | ALDH1A1SMN1; SMN2PKMC3AR1L3MBTL1 | |
| SCHEMBL3442919 | 0.79 | TLR2 (0.54) | ALDH1A1C3AR1RAB9AITGB3FOLH1 | |
| SCHEMBL9161634 | 0.79 | TLR2 (0.54) | ALDH1A1C3AR1RAB9AITGB3FOLH1 | |
| SCHEMBL29527346 | 0.78 | NAALAD2 (0.48) | ALDH1A1ERCC5FEN1CTNNB1WNT3A | |
| SCHEMBL29527715 | 0.78 | NAALAD2 (0.48) | ALDH1A1ERCC5FEN1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601370-B2 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES (US) | 2009-10-13 | — | — | US | disclosed |
| US-20090011078-A1 | NUTRITIONAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS | ABBOTT LABORATORIES (US) | 2009-01-08 | — | — | US | disclosed |
| US-7435431-B2 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES (US) | 2008-10-14 | — | — | US | disclosed |
| US-20080242592-A1 | METHOD FOR CONTROLLING BODY WEIGHT IN ESTROGEN-INSUFFICIENT WOMEN | ABBOTT LABORATORIES (US) | 2008-10-02 | — | — | US | disclosed |
| EP-1773364-B1 | NUTRITIONAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS | ABBOTT LAB (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2008076579-A2 | METHOD OF CONTROLLING BODY WEIGHT IN ESTROGEN-INSUFFICIENT WOMEN | ABBOT LABORATORIES (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20070098821-A1 | Method for controlling body weight in estrogen-insufficient women | ABBOTT LABORATORIES | 2007-05-03 | — | — | US | disclosed |
| US-20060040001-A1 | Nutritional compositions and methods for treating or preventing osteoporosis | ABBOTT LABORATORIES | 2006-02-23 | — | — | US | disclosed |