Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | C3AR1 | Q16581 | 4/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901461 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL3901457 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL1426405 | 0.82 | NPY4R (0.56) | — | |
| SCHEMBL9956085 | 0.81 | C3AR1 (0.40) | ALDH1A1SMN1; SMN2PKMKMT2AL3MBTL1 | |
| SCHEMBL9956081 | 0.81 | C3AR1 (0.40) | ALDH1A1SMN1; SMN2PKMKMT2AL3MBTL1 | |
| SCHEMBL25365176 | 0.81 | KMT2A (0.51) | ALDH1A1SMN1; SMN2PKMCTSLKMT2A | |
| SCHEMBL188589 | 0.81 | C3AR1 (0.52) | C3AR1FOLH1 | |
| SCHEMBL188590 | 0.81 | C3AR1 (0.52) | C3AR1FOLH1 | |
| SCHEMBL7925397 | 0.81 | C3AR1 (0.52) | C3AR1FOLH1 | |
| SCHEMBL14090780 | 0.80 | C3AR1 (0.49) | C3AR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066402-B | Peptide derivative and composition for promoting tear secretion containing the same | UNIV KINKI | 2013-11-06 | — | — | CN | disclosed |
| EP-2301951-B1 | PEPTIDE DERIVATIVE AND COMPOSITION FOR PROMOTING TEAR SECRETION COMPRISING THE SAME | UNIV KINKI (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-8383595-B2 | Peptide derivative and composition for promoting tear secretion comprising the same | KINKI UNIVERSITY (JP) | 2013-02-26 | — | — | US | disclosed |
| US-20110224154-A1 | PEPTIDE DERIVATIVE AND COMPOSITION FOR PROMOTING TEAR SECRETION COMPRISING THE SAME | KINKI UNIVERSITY (JP) | 2011-09-15 | — | — | US | disclosed |
| CN-102066402-A | Peptide derivative and composition for promoting tear secretion containing the same | UNIV KINKI | 2011-05-18 | — | — | CN | disclosed |
| EP-2301951-A1 | PEPTIDE DERIVATIVE AND COMPOSITION FOR PROMOTING TEAR SECRETION COMPRISING THE SAME | Kinki University (JP) | 2011-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224154-A1 | PEPTIDE DERIVATIVE AND COMPOSITION FOR PROMOTING TEAR SECRETION COMPRISING THE SAME | CFD, VIP, CSTB | ALDH1A1 4579/4885SMN1; SMN2 4778/4885PKM 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.