Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.65 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901539 | 1.00 | FAAH (0.65) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL17352280 | 0.98 | FAAH (0.69) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL17352281 | 0.98 | FAAH (0.69) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8696497 | 0.98 | FAAH (0.69) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8696500 | 0.98 | FAAH (0.69) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7902870 | 0.95 | FAAH (0.67) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7902868 | 0.95 | FAAH (0.67) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL1270704 | 0.92 | — | — | |
| SCHEMBL1270703 | 0.92 | — | — | |
| SCHEMBL13626153 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1762565-B1 | Alkyl substituted octennitrile derivatives | INT FLAVORS & FRAGRANCES INC (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1762565-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | ARNT, HCCS, AHR | FAAH 2389/4885SOAT1 1378/4885CYP1A2 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.