Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | UBE2M | P61081 | 6/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580583 | 0.87 | KMT2A (0.46) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11012013 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11017506 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11017509 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11012767 | 0.76 | KMT2A (0.51) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL907510 | 0.76 | KMT2A (0.51) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11012763 | 0.76 | KMT2A (0.51) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL19781780 | 0.76 | MEN1 (0.53) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL16615584 | 0.75 | RAB9A (0.51) | ALDH1A1KMT2AMEN1LMNATP53 | |
| SCHEMBL11012384 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | disclosed |