Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 5/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014046 | 1.00 | UCHL1 (0.52) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL2885604 | 0.92 | UCHL1 (0.47) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL1284259 | 0.86 | UCHL1 (0.67) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL23063791 | 0.86 | NOTUM (0.64) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL29535019 | 0.86 | UCHL1 (0.67) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL868581 | 0.84 | NOTUM (0.65) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| Potassium Ion SCHEMBL31605708 | 0.84 | UCHL1 (0.51) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL868725 | 0.84 | NOTUM (0.65) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL256728 | 0.84 | UCHL1 (0.51) | UCHL1NOTUMKDM1AHDAC1HDAC6 | |
| SCHEMBL31161382 | 0.84 | UCHL1 (0.51) | UCHL1NOTUMKDM1AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | UCHL1 4626/4885NOTUM 2224/4885KDM1A 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.