SCHEMBL29535019

SCHEMBL29535019

CC(C)(C)OC(=O)N1CCc2c(Br)cccc21

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 5/20 0.67
NOTUM Q6P988 7/20 0.49
KDM1A O60341 1/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
USP30 Q70CQ3 1/20 0.45
AR P10275 1/20 0.42
BCHE P06276 1/20 0.41
GPR119 Q8TDV5 1/20 0.41
HTR2C P28335 1/20 0.41
ABHD6 Q9BV23 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1284259 1.00 UCHL1 (0.67) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL20571008 0.92 UCHL1 (0.61) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL30147617 0.92 UCHL1 (0.61) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL31014046 0.86 UCHL1 (0.52) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL3902861 0.86 UCHL1 (0.52) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL23063791 0.86 NOTUM (0.64) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL25138052 0.85 UCHL1 (0.52) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL868725 0.84 NOTUM (0.65) UCHL1NOTUMKDM1AHDAC1HDAC6
Potassium Ion SCHEMBL31605708 0.84 UCHL1 (0.51) UCHL1NOTUMKDM1AHDAC1HDAC6
SCHEMBL868581 0.84 NOTUM (0.65) UCHL1NOTUMKDM1AHDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US disclosed
EP-4692057-A1 NOVEL B0AT1 INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2026-02-11 EP disclosed
US-20260001849-A1 NOVEL B0AT1 INHIBITOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-01-01 US disclosed
EP-4638441-A1 GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2025-10-29 EP disclosed
EP-4606799-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2025-08-27 EP disclosed
CN-120077040-A Compounds for SHP2 protein degradation and medical uses thereof 尤比克斯治疗公司 2025-05-30 CN disclosed
EP-4540240-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME Monte Rosa Therapeutics AG (CH) 2025-04-23 EP disclosed
WO-2024220937-A2 TYK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2024-10-24 WO disclosed
WO-2024210198-A1 NOVEL B0AT1 INHIBITOR 田辺三菱製薬株式会社 2024-10-10 WO disclosed
WO-2024133499-A1 GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES RHEINISCHE-FRIEDRICH-WILHELMS-UNIVERSITÄT BONN (DE) 2024-06-27 WO disclosed
WO-2024085699-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF 주식회사 유빅스테라퓨틱스 2024-04-25 WO disclosed
WO-2023244815-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
EP-4225742-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES Enliven Therapeutics, Inc. (US) 2023-08-16 EP disclosed
CN-115397467-A Therapeutic agent for tauopathy 住友制药株式会社 2022-11-25 CN disclosed
WO-2022076975-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN THERAPEUTICS, INC. (US) 2022-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001849-A1 NOVEL B0AT1 INHIBITOR BCAT1, BCAT2, BHMT UCHL1 1678/4885NOTUM 1891/4885KDM1A 1279/4885
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF PTPN6, PTPN1, PTPN11 UCHL1 1938/4885NOTUM 3917/4885KDM1A 2286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.