Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 4/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903021 | 0.84 | F10 (0.48) | F10F2CDK1CXCR3ADORA2A | |
| SCHEMBL3900223 | 0.81 | F10 (0.44) | F10F2CDK1CXCR3ADORA2A | |
| SCHEMBL3900221 | 0.81 | F10 (0.44) | F10F2CDK1CXCR3ADORA2A | |
| SCHEMBL3902456 | 0.77 | SCN9A (0.34) | CDK1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3903134 | 0.73 | F10 (0.71) | F10F2CXCR3MEN1ALDH1A1 | |
| SCHEMBL3903206 | 0.71 | CDK1 (0.39) | F10CDK1EGLN1ALDH1A1KMT2A | |
| SCHEMBL3903208 | 0.71 | CDK1 (0.39) | F10CDK1EGLN1ALDH1A1KMT2A | |
| SCHEMBL6553729 | 0.69 | CDK1 (0.38) | F10F2CDK1EGLN1ALDH1A1 | |
| SCHEMBL3899503 | 0.69 | NPC1 (0.53) | CDK1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5189193 | 0.67 | CDK1 (0.43) | F10CDK1ADORA2AEGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |