Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900223 | 1.00 | F10 (0.44) | F10F2CDK1ADORA2ACXCR3 | |
| SCHEMBL3903206 | 0.91 | CDK1 (0.39) | F10CDK1DRD3HSD17B10EGLN1 | |
| SCHEMBL3903208 | 0.91 | CDK1 (0.39) | F10CDK1DRD3HSD17B10EGLN1 | |
| SCHEMBL3903021 | 0.86 | F10 (0.48) | F10F2CDK1ADORA2ACXCR3 | |
| SCHEMBL3903019 | 0.81 | F10 (0.46) | F10F2CDK1ADORA2ACXCR3 | |
| SCHEMBL3899270 | 0.81 | GPR119 (0.48) | F10F2 | |
| SCHEMBL3899273 | 0.81 | GPR119 (0.48) | F10F2 | |
| SCHEMBL3894603 | 0.81 | RORC (0.40) | CDK1 | |
| SCHEMBL3894607 | 0.81 | RORC (0.40) | CDK1 | |
| Trifluoroacetic Acid SCHEMBL3898215 | 0.80 | CDK1 (0.38) | F10F2CDK1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |