Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900652 | 0.86 | RAB9A (0.46) | NPC1RAB9AKMT2ANOS3NOS1 | |
| SCHEMBL3896153 | 0.84 | F2 (0.46) | NPC1RAB9AKMT2ANOS3NOS1 | |
| SCHEMBL3897181 | 0.80 | F10 (0.60) | NPC1RAB9APOLBGAAHPGD | |
| SCHEMBL3900535 | 0.79 | NPC1 (0.43) | NPC1RAB9ATRPA1CDK1GFER | |
| SCHEMBL7566194 | 0.79 | NPC1 (0.75) | NPC1RAB9AKMT2APOLBMEN1 | |
| SCHEMBL14131854 | 0.77 | F10 (0.66) | NPC1KMT2APOLBHSP90AA1L3MBTL1 | |
| SCHEMBL3902858 | 0.76 | RAB9A (0.58) | NPC1RAB9AKMT2APOLBMEN1 | |
| SCHEMBL20971496 | 0.76 | SMN1; SMN2 (0.53) | NPC1RAB9AKMT2ANOS3NOS1 | |
| SCHEMBL13161985 | 0.75 | EGLN1 (0.52) | RAB9ATRPA1CDK1POLBMCHR1 | |
| SCHEMBL6359493 | 0.74 | KMT2A (0.59) | NPC1RAB9AKMT2ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |