Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123835 | 0.93 | KDM4E (0.35) | KDM4EALDH1A1POLBCYP1A2CYP2D6 | |
| SCHEMBL141765 | 0.91 | KDM4E (0.36) | KDM4EALDH1A1POLBCYP1A2CYP2D6 | |
| SCHEMBL20495376 | 0.89 | KDM4E (0.37) | KDM4EALDH1A1POLBCYP1A2CYP2D6 | |
| SCHEMBL1455088 | 0.85 | KDM4E (0.34) | KDM4EALDH1A1POLBCYP1A2CYP2D6 | |
| SCHEMBL28092643 | 0.83 | KDM4E (0.31) | KDM4EALDH1A1MEN1GAAHTT | |
| SCHEMBL4449821 | 0.79 | KDM4E (0.35) | KDM4EALDH1A1POLBCYP1A2CYP2D6 | |
| SCHEMBL1759454 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL628666 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1POLBMEN1GAA | |
| SCHEMBL15361137 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL56307 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1POLBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824865-B1 | HIGHLY REACTIVE ALPHA-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY | WACKER CHEMIE AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| EP-2021374-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | Leukocare AG (DE) | 2009-02-11 | — | — | EP | disclosed |
| EP-1824904-B1 | ALKOXYSILANE-TERMINATED PREPOLYMERS | WACKER CHEMIE AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007128550-A1 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES | LEUKOCARE AG (DE) | 2007-11-15 | — | — | WO | disclosed |