SCHEMBL628666

SCHEMBL628666

CO[Si](C)(CNC1CCCCC1)OC.CO[Si](CNC1CCCCC1)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 5/20 0.34
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.31
EPHX2 P34913 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56307 0.93 KDM4E (0.39) KDM4EMEN1KMT2AGAAHTT
SCHEMBL115823 0.91 KDM4E (0.40) KDM4EMEN1KMT2AGAAHTT
SCHEMBL18141888 0.89 KDM4E (0.42) KDM4EMEN1KMT2AGAAHTT
SCHEMBL20985092 0.89 ALDH1A1 (0.39) KDM4EMEN1KMT2AGAAHTT
SCHEMBL1455088 0.81 KDM4E (0.34) KDM4EMEN1KMT2AGAAHTT
SCHEMBL4776122 0.77 KDM4E (0.39) KDM4EMEN1KMT2AGAAHTT
SCHEMBL3903032 0.76 KDM4E (0.32) KDM4EMEN1KMT2AGAAHTT
SCHEMBL28495871 0.76 KDM4E (0.43) KDM4EMEN1KMT2AGAAHTT
SCHEMBL628667 0.74 KDM4E (0.32) KDM4EMEN1KMT2AGAAHTT
SCHEMBL123835 0.74 KDM4E (0.35) KDM4EMEN1KMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2145909-B1 Method for producing blocked alcohols SIKA TECHNOLOGY AG (CH) 2012-02-22 EP disclosed
EP-2145909-A1 Method for producing blocked alcohols Sika Technology AG (CH) 2010-01-20 EP disclosed