Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006048 | 0.87 | MYC (0.53) | KDM4ELMNAALDH1A1CTNNB1WNT3A | |
| SCHEMBL2417966 | 0.87 | PKM (0.43) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL21384935 | 0.83 | KDM4E (0.49) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL1133289 | 0.80 | MGAM (0.47) | MAPTKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL7510205 | 0.77 | MAPT (0.46) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL27204316 | 0.74 | BAZ2B (0.53) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL10549571 | 0.73 | KDM4E (0.46) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL3902060 | 0.73 | BRD4 (0.44) | MAPTKDM4EALDH1A1S1PR4MYC | |
| SCHEMBL24573794 | 0.73 | HPGD (0.56) | KDM4EALDH1A1GAAGLASMN1; SMN2 | |
| SCHEMBL6371894 | 0.73 | CD44 (0.45) | MAPTKDM4EALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |