Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596567 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1LMNAL3MBTL1HCRTR1 | |
| SCHEMBL2417969 | 0.85 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL27204316 | 0.84 | BAZ2B (0.53) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL21384934 | 0.83 | KDM4E (0.49) | MAPTKDM4EALDH1A1GAAHCRTR1 | |
| SCHEMBL22261511 | 0.83 | ALDH1A1 (0.53) | MAPTKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL25550174 | 0.80 | MYC (0.44) | KDM4EALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL3903077 | 0.77 | MAPT (0.46) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL27684614 | 0.75 | TMIGD3 (0.46) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28080111 | 0.74 | KDM4E (0.49) | MAPTKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8444051 | 0.74 | MEN1 (0.44) | MAPTKDM4EALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |