⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909488 | 0.80 | — | — | |
| SCHEMBL8472498 | 0.72 | — | — | |
| SCHEMBL505953 | 0.69 | — | — | |
| SCHEMBL6223633 | 0.69 | — | — | |
| SCHEMBL11329917 | 0.69 | PTGS1 (0.45) | — | |
| SCHEMBL28826346 | 0.69 | KDM4E (0.43) | — | |
| SCHEMBL24129457 | 0.67 | — | — | |
| SCHEMBL249947 | 0.67 | LMNA (0.50) | — | |
| SCHEMBL10337030 | 0.67 | — | — | |
| SCHEMBL10644055 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306126-A1 | Indole Derivatives | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090118336-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | claimed |
| EP-2029593-A1 | INDOLE DERIVATIVES | AstraZeneca AB (SE) | 2009-03-04 | — | — | EP | claimed |
| EP-2016068-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | AstraZeneca AB (SE) | 2009-01-21 | — | — | EP | claimed |
| WO-2007135398-A1 | INDOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-11-29 | — | — | WO | claimed |
| WO-2007129052-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | claimed |
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | claimed |
| US-20090306126-A1 | Indole Derivatives | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
| US-20090118336-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | disclosed |
| US-20090076009-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |
| EP-2029593-A1 | INDOLE DERIVATIVES | AstraZeneca AB (SE) | 2009-03-04 | — | — | EP | disclosed |
| EP-2016075-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2009-01-21 | — | — | EP | disclosed |
| EP-2016068-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | AstraZeneca AB (SE) | 2009-01-21 | — | — | EP | disclosed |
| EP-0807268-A1 | CROSSLINKED TINTED POLYMERS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996024076-A1 | CROSSLINKED TINTED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |
| EP-0564583-B1 | METHOD FOR TINTING A HYDROPHILIC POLYMER | ALLERGAN INC (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5151106-A | Mixing a dichlorotriazine reactive polymer and reaction with polymer in the presence of a catalyst and molding to form contact lenses | ALLERGAN, INC. (US) | 1992-09-29 | — | — | US | disclosed |
| US-4559059-A | REACTIVE DYES BONDED TO POLYMER | CIBA-GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| US-4553975-A | REACTING A DYE WITH COPOLYMER GEL | CIBA GEIGY CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
| US-4468229-A | Tinted contact lenses and a method for their preparation with reactive dyes | CIBA-GEIGY CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |