SCHEMBL249947

SCHEMBL249947

O=S(=O)(O)CCO.O=S(=O)(O)CCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
BLM P54132 2/20 0.50
PTGS1 P23219 1/20 0.50
PDE4A P27815 1/20 0.50
SLC6A6 P31641 1/20 0.50
CYP2C19 P33261 1/20 0.50
APP P05067 1/20 0.45
POLB P06746 3/20 0.37
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 1/20 0.37
ALOX15 P16050 1/20 0.37
BRCA1 P38398 1/20 0.37
HTT P42858 1/20 0.37
GMNN O75496 1/20 0.37
PKM P14618 1/20 0.37
THPO P40225 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL827 1.00
SCHEMBL8780216 0.96 LMNA (0.47) LMNABLMPTGS1PDE4ASLC6A6
SCHEMBL1177405 0.96
Sulfuric Acid SCHEMBL9751183 0.96 LMNA (0.47) LMNABLMPTGS1PDE4ASLC6A6
SCHEMBL1138826 0.96
SCHEMBL11516591 0.96 LMNA (0.47) LMNABLMPTGS1PDE4ASLC6A6
SCHEMBL1138506 0.96
SCHEMBL1304651 0.96
Bromide SCHEMBL20595015 0.96
SCHEMBL9001614 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680182-A1 NEW SOLID COSMETIC COMPOSITIONS AND USE THEREOF FOR HYGIENE OF THE SKIN OR HAIR Pierre Fabre Dermo-Cosmétique (FR) 2026-01-21 EP disclosed
CN-119033822-A Compositions and methods for inhibiting seizures 加利福尼亚大学董事会 2024-11-29 CN disclosed
WO-2024189052-A1 NEW SOLID COSMETIC COMPOSITIONS AND USE THEREOF FOR HYGIENE OF THE SKIN OR HAIR Pierre Fabre Dermo-Cosmétique (FR) 2024-09-19 WO disclosed
CN-110325196-B Compositions and methods for inhibiting seizures 加利福尼亚大学董事会 2024-08-27 CN disclosed
CN-111801121-B 2-PMPA prodrugs for healthy tissue protection during PSMA-targeted cancer imaging or radiation therapy 约翰霍普金斯大学 2023-12-01 CN disclosed
CN-117062607-A Methyl substituted pyridine and pyridazine compounds, derivatives thereof and methods of use thereof 拉堤果生物医疗股份有限公司 2023-11-14 CN disclosed
US-20230277484-A1 COMPOSITIONS AND METHODS TO PROMOTE BRAIN HEALTH Guardian Biosciences, LLC (US) 2023-09-07 US disclosed
WO-2023167989-A2 COMPOSITIONS AND METHODS TO PROMOTE BRAIN HEALTH Guardian Biosciences, LLC (US) 2023-09-07 WO disclosed
EP-3322417-B1 TARGETING EMOPAMIL BINDING PROTEIN (EBP) WITH SMALL MOLECULES THAT INDUCE AN ABNORMAL FEEDBACK RESPONSE BY LOWERING ENDOGENOUS CHOLESTEROL BIOSYNTHESIS UNIV TEXAS (US) 2023-08-23 EP disclosed
US-11725056-B2 Methods for targeting the immune checkpoint PD1 pathway for treating pulmonary fibrosis CEDARS-SINAI MEDICAL CENTER (US) 2023-08-15 US disclosed
US-20070191371-A1 HETEROCYCLIC MODULATORS OF PPAR KALYPSYS, INC. (US) 2007-08-16 US disclosed
US-7235661-B2 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction ABBOTT LABORATORIES (US) 2007-06-26 US disclosed
US-20060264476-A1 Farnesyltransferase Inhibitors ABBVIE INC. 2006-11-23 US disclosed
US-20060199851-A1 Novel compounds that are useful for improving pharmacokinetics ABBVIE INC. 2006-09-07 US disclosed
US-20060199864-A1 Selection of pH-dependent compounds for in vivo therapy EMORY UNIVERSITY 2006-09-07 US disclosed
US-20060172995-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction ABBVIE INC. 2006-08-03 US disclosed
EP-1643948-A1 DIFFUSION LAYER MODULATED SOLIDS Pharmacia & Upjohn Company LLC (US) 2006-04-12 EP disclosed
US-20050042291-A1 Diffusion layer modulated solids HAWLEY MICHAEL (US) 2005-02-24 US disclosed
WO-2005004763-A1 DIFFUSION LAYER MODULATED SOLIDS PHARMACIA & UPJOHN COMPANY LLC. (US) 2005-01-20 WO disclosed
US-6008303-A Polymers suitable as dispersing resins BASF AKTIENGESELLSCHAFT (DE) 1999-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191371-A1 HETEROCYCLIC MODULATORS OF PPAR PPARG, PPARD, PPARA LMNA 2210/4885BLM 3393/4885PTGS1 335/4885
US-20060199851-A1 Novel compounds that are useful for improving pharmacokinetics CYP11B1, CYP11B2, CYP7A1 LMNA 4776/4885BLM 4111/4885PTGS1 125/4885
US-20060172995-A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction CYP19A1, CYP17A1, DDC LMNA 3391/4885BLM 1350/4885PTGS1 1535/4885
US-20060264476-A1 Farnesyltransferase Inhibitors FNTB, FNTA, FDPS LMNA 3187/4885BLM 3079/4885PTGS1 1334/4885
US-20060199864-A1 Selection of pH-dependent compounds for in vivo therapy PHGDH, ASAH2, HRH2 LMNA 2505/4885BLM 2594/4885PTGS1 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.