Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | SCN1A | P35498 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996545 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL3904458 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL2066147 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL1422822 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL27511961 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL6997071 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| SCHEMBL7000444 | 0.80 | SLC6A2 (0.51) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7927468 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL16702791 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7864529 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRM2SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069132-B1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-10-01 | — | — | EP | disclosed |
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |
| EP-1069132-A1 | Bicyclic derivatives of amino-pyrazinones, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-01-17 | — | — | EP | disclosed |