Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.61 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.61 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.61 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.61 |
| ▸ | SRC | P12931 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805694 | 0.79 | EGFR (0.60) | MEN1KMT2AEGFRPIM1TOP1 | |
| SCHEMBL143878 | 0.76 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL7805666 | 0.74 | EGFR (0.54) | MEN1KMT2AEGFRPIM1TOP1 | |
| SCHEMBL3417492 | 0.73 | EGFR (0.76) | MEN1KMT2AEGFRPIM1TOP1 | |
| SCHEMBL28575370 | 0.73 | MEN1 (0.72) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3886882 | 0.72 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL8947495 | 0.71 | EGFR (0.73) | MEN1KMT2AEGFRPIM1TOP1 | |
| SCHEMBL8996338 | 0.71 | MEN1 (0.55) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL7805708 | 0.71 | EGFR (0.54) | MEN1KMT2AEGFRPIM1TOP1 | |
| SCHEMBL31435387 | 0.70 | MAPT (0.70) | FGFR1FGFR2FGFR4FGFR3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |