SCHEMBL8947495

SCHEMBL8947495

COc1cccc2c1C(=O)c1c(OC)cccc1C2=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.73
PIM1 P11309 1/20 0.73
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
ELANE P08246 8/20 0.70
MAPT P10636 4/20 0.62
ALDH1A1 P00352 3/20 0.62
APAF1 O14727 1/20 0.62
MITF O75030 1/20 0.62
LMNA P02545 1/20 0.62
HTT P42858 1/20 0.62
RAB9A P51151 3/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
KDM4E B2RXH2 1/20 0.61
USP2 O75604 1/20 0.61
DUSP3 P51452 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
TOP1 P11387 1/20 0.60
CTSG P08311 1/20 0.57
NPC1 O15118 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417492 0.93 EGFR (0.76) EGFRPIM1MEN1KMT2AELANE
SCHEMBL612831 0.92 MAPT (0.74) EGFRPIM1MEN1KMT2AELANE
SCHEMBL10974170 0.92 EGFR (0.74) EGFRPIM1MEN1KMT2AELANE
SCHEMBL7792566 0.89 EGFR (0.71) EGFRPIM1MEN1KMT2AELANE
SCHEMBL31435387 0.89 MAPT (0.70) EGFRPIM1MEN1KMT2AELANE
SCHEMBL8382011 0.89 MEN1 (0.84) EGFRPIM1MEN1KMT2AELANE
SCHEMBL10811289 0.89 EGFR (0.61) EGFRPIM1MEN1KMT2AELANE
SCHEMBL28575370 0.89 MEN1 (0.72) EGFRPIM1MEN1KMT2AELANE
SCHEMBL5816933 0.88 EGFR (0.64) EGFRPIM1MEN1KMT2AELANE
SCHEMBL9878296 0.86 ELANE (0.60) EGFRPIM1MEN1KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101538262-A Bryoanthrathiophenic substance and synthetic method thereof UNIV PLA 3RD MILITARY MEDICAL 2009-09-23 CN claimed
CN-101348478-A Preparation of methyl bryoanthrathiophene and analogues thereof UNIV PLA 3RD MILITARY MEDICAL (CN) 2009-01-21 CN claimed
EP-0015486-B1 PROCESS FOR THE PREPARATION OF 4,5-DINITRO-1,8-DIHYDROXYANTHRAQUINONE BAYER AG (DE) 1984-01-04 EP claimed
US-4342701-A Process for the preparation of 4,5-dinitro-1,8-dihydroxyanthraquinone BAYER AKTIENGESELLSCHAFT (DE) 1982-08-03 US claimed
EP-0015486-A2 Process for the preparation of 4,5-dinitro-1,8-dihydroxyanthraquinone BAYER AG (DE) 1980-09-17 EP claimed
JP-53066941-A None JP disclosed
US-11658322-B2 Membranes and anion conductive polymers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-23 US disclosed
EP-3369780-B1 METHOD FOR MANUFACTURING SUBSTRATE AND METHOD FOR MANUFACTURING LIGHT EMITTING ELEMENT USING SAME TORAY INDUSTRIES (JP) 2022-10-26 EP disclosed
US-20210135265-A1 ANION CONDUCTIVE POLYMERS AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-05-06 US disclosed
CN-108291087-B Method for manufacturing substrate and method for manufacturing light-emitting element using same 东丽株式会社 2020-09-15 CN disclosed
US-10544090-B2 Anthraquinone analogs and methods of making and using thereof GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-01-28 US disclosed
CN-110526827-A Anthraquinone analogs and its preparation and application UNIV GEORGIA STATE RES FOUND 2019-12-03 CN disclosed
US-4258124-A Photosensitive composition MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1981-03-24 US disclosed
EP-0015486-A2 Process for the preparation of 4,5-dinitro-1,8-dihydroxyanthraquinone BAYER AG (DE) 1980-09-17 EP disclosed
EP-0014367-A1 Process for the preparation of dimethoxyanthraquinones BAYER AG (DE) 1980-08-20 EP disclosed
EP-0013006-A1 Developer composition for lithographic printing plates MITSUBISHI KASEI CORPORATION (JP) 1980-07-09 EP disclosed
EP-0009223-A2 Photosensitive composition MITSUBISHI KASEI CORPORATION (JP) 1980-04-02 EP disclosed
JP-S5366941-A PREPARATION OF ANTHROQUINONE DISPERSION DYES MITSUBISHI CHEM IND LTD 1978-06-14 JP disclosed
US-4080370-A Process for producing high purity methoxyanthraquinones MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JA) 1978-03-21 US disclosed
US-3983145-A Use of alpha-di(lower alkoxy) anthraquinones in the synthesis of Alizarin Saphirols TOMS RIVER CHEMICAL CORPORATION (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10544090-B2 Anthraquinone analogs and methods of making and using thereof PCNA, KRAS, RECQL EGFR 2701/4885PIM1 3546/4885MEN1 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.