Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890633 | 0.84 | FGFR1 (0.48) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3904565 | 0.72 | FGFR1 (0.61) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL143878 | 0.72 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL8052814 | 0.70 | HTR7 (0.47) | RAB9ANPC1THRBALDH1A1MAPT | |
| SCHEMBL13937653 | 0.69 | FGFR1 (0.54) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL198463 | 0.68 | IDO1 (0.52) | ALDH1A1MAPTSMN1; SMN2GAATSHR | |
| SCHEMBL2427784 | 0.67 | ALDH1A1 (0.57) | MEN1KMT2AEGFRALDH1A1TSHR | |
| SCHEMBL29548152 | 0.67 | ALDH1A1 (0.57) | MEN1KMT2AEGFRALDH1A1TSHR | |
| SCHEMBL667702 | 0.66 | ALDH1A1 (0.47) | MEN1KMT2AHSP90AA1RAB9ANPC1 | |
| SCHEMBL4324495 | 0.66 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |