SCHEMBL3905949

SCHEMBL3905949

CCCCCCCCCc1ccc2c(c1CCCCCCCCC)C(c1ccccc1)C(=O)O2

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
CSNK2B P67870 2/20 0.43
CSNK2A1 P68400 2/20 0.43
CYP1A1 P04798 1/20 0.37
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
CYSLTR2 Q9NS75 6/20 0.36
CYSLTR1 Q9Y271 6/20 0.36
LIPG Q9Y5X9 1/20 0.35
PIP5K1A Q99755 1/20 0.34
TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454649 0.86 GAA (0.46) GAACSNK2BCSNK2A1CYP1A1PIP5K1A
SCHEMBL3896297 0.86 CSNK2B (0.41) GAACSNK2BCSNK2A1CYP1A1NR1H2
SCHEMBL3897037 0.86 CSNK2B (0.41) GAACSNK2BCSNK2A1CYP1A1NR1H2
SCHEMBL4449574 0.81 GAA (0.42) GAACSNK2BCSNK2A1CYP1A1NR1H2
Nonane SCHEMBL27663344 0.74 GAA (0.56) GAA
SCHEMBL2229814 0.74 KMT2A (0.49) CYSLTR2CYSLTR1
SCHEMBL3896295 0.71 CYSLTR2 (0.47) CYP1A1NR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL11708641 0.69 ELANE (0.45) CYP1A1NR1H2NR1H3LIPGTYR
SCHEMBL1557118 0.68 GAA (0.33) GAACSNK2BCSNK2A1CYP1A1
SCHEMBL323496 0.68 ESR1 (0.37) CSNK2BCSNK2A1CYP1A1PIP5K1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US claimed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO claimed
EP-1692150-A4 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORP (US) 2009-02-25 EP disclosed
US-7470735-B2 Phenol-free phosphites DOVER CHEMICAL CORPORATION (US) 2008-12-30 US disclosed
US-7342060-B2 Process for manufacture of pentaerythritol diphosphites DOVER CHEMICAL CORPORATION (US) 2008-03-11 US disclosed
EP-1692150-A2 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES Dover Chemical Corporation (US) 2006-08-23 EP disclosed
WO-2005113665-A2 PHENOL-FREE PHOSPHITES DOVER CHEMICAL CORPORATION (US) 2005-12-01 WO disclosed
WO-2005060500-A2 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORPORATION (US) 2005-07-07 WO disclosed
US-20050131244-A1 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES DOVER CHEMICAL CORPORATION (US) 2005-06-16 US disclosed
US-20040180999-A1 PHENOL-FREE PHOSPHITES DOVER CHEMICAL CORPORATION (US) 2004-09-16 US disclosed
US-6770693-B2 COMPRISING BIS-(2,4-DICUMYLPHENYL) PENTAERYTHRITOL DIPHOSPHITE AND HINDERED PHENOL ANTIOXIDANTS USEFUL AS STABILIZERS AGAINST THERMOOXIDATIVE DEGRADATION OF POLYMERS DURING MELT PROCESSING DOVE CHEMICAL CORPORATION 2004-08-03 US disclosed
US-20020040081-A1 Blends of phosphites and antioxidants DOVER CHEMICAL 2002-04-04 US disclosed
US-6224791-B1 PHENYLBENZOFURAN-2-ONE WITH PHOSPHITE DOVER CHEMICAL CORPORATION 2001-05-01 US disclosed
WO-1999003915-A1 LACTONE/PHOSPHITE BLENDS DOVER CHEMICAL CORPORATION (US) 1999-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131244-A1 PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES GNPAT, DCTPP1, DERA GAA 2344/4885CSNK2B 3158/4885CSNK2A1 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.