Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504158 | 0.76 | PADI4 (0.53) | ERN1PADI4ALOX15MAPTMEN1 | |
| SCHEMBL2368058 | 0.74 | CA1 (0.41) | ALOX15CYP3A4TSHRTDP1GPR35 | |
| SCHEMBL3908409 | 0.68 | TDP1 (0.36) | ERN1PADI4PRMT1TDP1MEN1 | |
| SCHEMBL680308 | 0.67 | ERN1 (0.48) | ERN1MAPT | |
| SCHEMBL6782431 | 0.67 | ERN1 (0.48) | ERN1MAPT | |
| SCHEMBL19305533 | 0.67 | ERN1 (0.77) | ERN1ALOX15 | |
| SCHEMBL6659658 | 0.66 | ERN1 (0.47) | ERN1PADI4CYP3A4TSHRTDP1 | |
| SCHEMBL28441918 | 0.66 | ERN1 (0.44) | ERN1PADI4CYP3A4MAPT | |
| SCHEMBL12483710 | 0.65 | ALOX15 (0.46) | ALOX15CYP3A4TSHRTDP1MAPT | |
| SCHEMBL12484114 | 0.65 | ALOX15 (0.46) | ALOX15CYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018844-A2 | Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds | Henkel AG & Co. KGaA (DE) | 2009-01-28 | — | — | EP | claimed |