Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782431 | 0.91 | ERN1 (0.48) | ERN1PRKDCBACE1LMNATRIM24 | |
| SCHEMBL2336761 | 0.88 | ERN1 (0.50) | ERN1PRKDCLMNAPIM1TRIM24 | |
| SCHEMBL18927374 | 0.86 | ERN1 (0.54) | ERN1PIM1TRIM24TRIM33CISD1 | |
| SCHEMBL1162124 | 0.82 | PRKDC (0.56) | ERN1PRKDCLMNATRIM24TRIM33 | |
| SCHEMBL1860423 | 0.81 | ERN1 (0.54) | ERN1PRKDCTRIM24TRIM33CISD1 | |
| SCHEMBL30064066 | 0.81 | ERN1 (0.54) | ERN1PRKDCTRIM24TRIM33CISD1 | |
| SCHEMBL565838 | 0.80 | ERN1 (0.44) | ERN1PRKDCLMNAPIM1TRIM24 | |
| SCHEMBL3562577 | 0.80 | ERN1 (0.44) | ERN1PIM1TRIM24TRIM33 | |
| SCHEMBL31260455 | 0.80 | ERN1 (0.44) | ERN1PRKDCPIM1TRIM24TRIM33 | |
| SCHEMBL8388616 | 0.80 | ERN1 (0.50) | ERN1PRKDCLMNAPIM1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964985-B | Preparation method of wear-resistant high-strength plastic | 广东聚邦兴材科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-117987982-A | Anti-mite antistatic fabric and preparation method thereof | 左孝红 | 2024-05-07 | — | — | CN | claimed |
| CN-117964985-A | Preparation method of wear-resistant high-strength plastic | 苏州赛荣建筑装饰工程有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116554610-B | Wear-resistant high-strength plastic and preparation method thereof | 东莞市德源新材料有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-116554610-A | Wear-resistant high-strength plastic and preparation method thereof | 苏州赛荣建筑装饰工程有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-114250027-B | High-performance flame-retardant antistatic powder coating and preparation method thereof | 山东信科新材料有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114250027-A | High-performance flame-retardant antistatic powder coating and preparation method thereof | 山东信科新材料有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-117964985-B | Preparation method of wear-resistant high-strength plastic | 广东聚邦兴材科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117987982-A | Anti-mite antistatic fabric and preparation method thereof | 左孝红 | 2024-05-07 | — | — | CN | disclosed |
| CN-117964985-A | Preparation method of wear-resistant high-strength plastic | 苏州赛荣建筑装饰工程有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-116554610-B | Wear-resistant high-strength plastic and preparation method thereof | 东莞市德源新材料有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11952364-B2 | TRK inhibitors useful as anticancer drugs | TYLIGAND BIOSCIENCE (SHANGHAI) LIMITED (CN) | 2024-04-09 | — | — | US | disclosed |
| CN-116554610-A | Wear-resistant high-strength plastic and preparation method thereof | 苏州赛荣建筑装饰工程有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-2310382-A1 | AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET | Eli Lilly & Company (US) | 2011-04-20 | — | — | EP | disclosed |
| US-20110082295-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-04-07 | — | — | US | disclosed |
| EP-2305629-A1 | THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | Tokyo Institute of Technology (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| WO-2010011538-A1 | AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET | ELI LILLY AND COMPANY (US) | 2010-01-28 | — | — | WO | disclosed |
| US-20100022529-A1 | AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET | ELI LILLY AND COMPANY | 2010-01-28 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | ERN1 2254/4885PRKDC 4869/4885BACE1 1/4885 |
| US-11952364-B2 | TRK inhibitors useful as anticancer drugs | NTRK1, NTRK3, MUSK | ERN1 448/4885PRKDC 87/4885BACE1 3959/4885 |
| US-20110082295-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | ERN1 1672/4885PRKDC 4795/4885BACE1 1/4885 |
| US-20100022529-A1 | AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET | MET, MYCBP, MYC | ERN1 2134/4885PRKDC 850/4885BACE1 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.