Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711456 | 0.86 | DPP4 (0.50) | MAPK14DPP4CYP1A2CYP2C19MAPK13 | |
| SCHEMBL3911088 | 0.83 | TAAR1 (0.50) | MAOBTAAR1DPP4CYP1A2SYK | |
| SCHEMBL3719145 | 0.81 | TRPV1 (0.47) | MAPK14CYP1A2CYP2C19BCHEMAPK10 | |
| SCHEMBL6579440 | 0.80 | NPC1 (0.40) | MAPK14MYCTRPV1 | |
| SCHEMBL3907000 | 0.80 | DPP4 (0.44) | TAAR1DPP4CYP1A2CYP2C19HRH1 | |
| Hydrochloric Acid SCHEMBL9030551 | 0.79 | TRPV1 (0.46) | MAPK14CYP1A2CYP2C19BCHEMAPK10 | |
| SCHEMBL3708397 | 0.79 | MAPK14 (0.43) | MAPK14DPP4CYP1A2CYP2C19MAPK13 | |
| SCHEMBL3906092 | 0.77 | DPP4 (0.55) | MAOBTAAR1DPP4HRH1 | |
| SCHEMBL30211300 | 0.76 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11TGFBR1 | |
| SCHEMBL30007391 | 0.76 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |