Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905562 | 1.00 | FPR2 (0.41) | FPR2CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL21144798 | 0.85 | MAPK1 (0.50) | FPR2CYP1A2CYP2D6MMECYP3A4 | |
| SCHEMBL3901670 | 0.85 | MAPK1 (0.50) | FPR2CYP1A2CYP2D6MMECYP3A4 | |
| SCHEMBL21144797 | 0.85 | MAPK1 (0.50) | FPR2CYP1A2CYP2D6MMECYP3A4 | |
| SCHEMBL27525436 | 0.78 | ATM (0.53) | CYP3A4 | |
| SCHEMBL27531117 | 0.78 | ATM (0.53) | CYP3A4 | |
| SCHEMBL27786644 | 0.76 | CYP1A2 (0.58) | CYP1A2CYP2D6APEX1PMP22ALDH1A1 | |
| SCHEMBL18546526 | 0.73 | FPR2 (0.48) | FPR2 | |
| SCHEMBL298697 | 0.73 | FPR2 (0.48) | FPR2 | |
| SCHEMBL2074452 | 0.72 | CTSC (0.55) | CYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |