Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905364 | 1.00 | BHMT (0.41) | BHMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4397917 | 0.85 | GABRP (0.46) | BHMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10212359 | 0.85 | GABRP (0.46) | BHMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL12132308 | 0.85 | GABRP (0.46) | BHMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27748429 | 0.83 | BHMT (0.40) | BHMTGABRPGABRDGABRA1GABRB1 | |
| Aspartic Acid SCHEMBL23454434 | 0.80 | SLC7A5 (0.58) | BHMTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Aspartic Acid SCHEMBL464907 | 0.80 | SLC7A5 (0.58) | BHMTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Aspartic Acid SCHEMBL22092469 | 0.80 | SLC7A5 (0.58) | BHMTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Aspartic Acid SCHEMBL939864 | 0.80 | SLC7A5 (0.58) | BHMTSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Aspartic Acid SCHEMBL464908 | 0.80 | SLC7A5 (0.58) | BHMTSLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258099-B2 | Peptide capable of inhibiting the peptidyl prolyl isomerase activity of peptidyl-prolyl cis-trans isomerases; cancer or neurodegenerative disease | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-09-04 | — | — | US | disclosed |
| JP-2009062326-A | INTERLEUKIN 4 PRODUCTION INHIBITOR | KYOWA HAKKO BIO CO LTD | 2009-03-26 | — | — | JP | disclosed |
| WO-2009016025-A1 | PROCESS FOR THE SYNTHESIS OF NA- BETA-ALANINATE AND CALCIUM PANTOTHENATE | DSM IP ASSETS B.V. (NL) | 2009-02-05 | — | — | WO | disclosed |
| US-20080214470-A1 | Peptide capable of inhibiting the peptidyl prolyl isomerase activity of peptidyl-prolyl cis-trans isomerases; cancer or neurodegenerative disease | VERNALIS PLC (GB) | 2008-09-04 | — | — | US | disclosed |
| EP-1776130-A2 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Vernalis PLC (GB) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006019982-A2 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | VERNALIS PLC (GB) | 2006-02-23 | — | — | WO | disclosed |
| EP-0220245-B1 | METHOD FOR DETERMINING MIMOTOPES | COSELCO MIMOTOPES PTY. LTD. (AU) | 1992-07-08 | — | — | EP | disclosed |
| US-4833092-A | Method for determining mimotopes | COMMONWEALTH SERUM LABORATORIES COMMISSION (AU) | 1989-05-23 | — | — | US | disclosed |
| EP-0220245-A4 | METHOD FOR DETERMINING MIMOTOPES. | COMMW SERUM LAB COMMISSION (AU) | 1988-01-26 | — | — | EP | disclosed |
| EP-0220245-A1 | METHOD FOR DETERMINING MIMOTOPES. | COMMW SERUM LAB COMMISSION (AU) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006487-A1 | METHOD FOR DETERMINING MIMOTOPES | COMMONWEALTH SERUM LABORATORIES COMMISSION (AU) | 1986-11-06 | — | — | WO | disclosed |