Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26268659 | 0.85 | TAAR1 (0.53) | TAAR1GPR84MAPTHIF1ACNR1 | |
| SCHEMBL5544074 | 0.85 | TAAR1 (0.53) | TAAR1L3MBTL1GPR84HIF1ACNR1 | |
| SCHEMBL26268493 | 0.85 | TAAR1 (0.62) | TAAR1L3MBTL1GPR84MAPTHIF1A | |
| SCHEMBL7784561 | 0.81 | TAAR1 (0.49) | TAAR1GPR84MAPTHIF1ACNR1 | |
| SCHEMBL26269306 | 0.81 | TAAR1 (0.53) | TAAR1L3MBTL1GPR84ALDH1A1MAPT | |
| SCHEMBL7988500 | 0.79 | RAB9A (0.65) | L3MBTL1MAPTHIF1AFFAR1RAB9A | |
| SCHEMBL6249041 | 0.79 | L3MBTL1 (0.44) | TAAR1L3MBTL1ALDH1A1MAPTCNR1 | |
| SCHEMBL10834316 | 0.79 | TAAR1 (0.69) | TAAR1GPR84HIF1ACNR1RAB9A | |
| SCHEMBL3903026 | 0.78 | TAAR1 (0.62) | TAAR1L3MBTL1GPR84ALDH1A1MAPT | |
| SCHEMBL5438535 | 0.77 | TAAR1 (0.41) | TAAR1L3MBTL1GPR84ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |