Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729373 | 0.89 | ACHE (0.46) | ACP3ACHEALDH1A1GAAL3MBTL1 | |
| SCHEMBL9729576 | 0.89 | ACP3 (0.46) | ACP3ALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL1515743 | 0.84 | ACP3 (0.50) | ACP3ACHEGAAL3MBTL1AOC3 | |
| SCHEMBL1515745 | 0.84 | ACP3 (0.50) | TRPM8ACP3ALDH1A1MEN1KMT2A | |
| Methyl Alcohol SCHEMBL11234402 | 0.83 | ACP3 (0.50) | TRPM8ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL11152058 | 0.82 | ACP3 (0.41) | ACP3ALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL21778081 | 0.82 | ACP3 (0.41) | ACP3ALDH1A1AOC3MEN1KMT2A | |
| SCHEMBL3905384 | 0.79 | ACP3 (0.40) | TRPM8ACP3ALDH1A1GAAAOC3 | |
| SCHEMBL18240783 | 0.79 | TRPM8 (0.43) | TRPM8ACP3KCNK3KCNK9ALDH1A1 | |
| SCHEMBL18240782 | 0.79 | TRPM8 (0.43) | TRPM8ACP3KCNK3KCNK9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |