Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612576 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL2127885 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL29612602 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL2125158 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL2125161 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5097585 | 0.84 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL1376884 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3912064 | 0.80 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL3911984 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL2127265 | 0.78 | PTGS2 (0.73) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592680-B9 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2009-03-25 | — | — | EP | claimed |
| EP-1592680-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2008-05-07 | — | — | EP | claimed |
| EP-1263751-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2002-12-11 | — | — | EP | claimed |
| WO-2001068633-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2001-09-20 | — | — | WO | claimed |