Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612602 | 1.00 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL2127885 | 1.00 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL29612576 | 1.00 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL2125161 | 1.00 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL3912064 | 0.91 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL29612982 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL2125358 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL2127265 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL29612578 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL2125355 | 0.89 | PTGS2 (0.73) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052180-A1 | COMBINATIONS COMPRISING DHODH INHIBITORS AND COX INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-26 | — | — | WO | claimed |
| EP-2444086-A1 | Combinations comprising DHODH inhibitors and COX inhibitors | Almirall, S.A. (ES) | 2012-04-25 | — | — | EP | claimed |
| US-7582676-B2 | 2-phenylpyran-4-one derivatives as selective COX-2 inhibitors | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-09-01 | — | — | US | claimed |
| EP-1592680-B9 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2009-03-25 | — | — | EP | claimed |
| EP-1592680-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2008-05-07 | — | — | EP | claimed |
| US-20060142380-A1 | 2-Phenylpyran-4-one derivatives as selective cox-2 inhibitors | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-29 | — | — | US | claimed |
| EP-1592680-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | Almirall Prodesfarma, S.A. (ES) | 2005-11-09 | — | — | EP | claimed |
| WO-2004072058-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-26 | — | — | WO | claimed |
| CN-114159421-B | Pharmaceutical composition comprising dimethyl fumarate | 阿尔米雷尔有限公司 | 2023-08-25 | — | — | CN | disclosed |
| US-11602515-B2 | Pharmaceutical compositions comprising dimethyl fumarate | ALMIRALL, S.A. (ES) | 2023-03-14 | — | — | US | disclosed |
| CN-114159421-A | Pharmaceutical composition comprising dimethyl fumarate | 阿尔米雷尔有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20210330628-A1 | Pharmaceutical Compositions Comprising Dimethyl Fumarate | ALMIRALL, S.A. (ES) | 2021-10-28 | — | — | US | disclosed |
| EP-3079666-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIMETHYL FUMARATE | ALMIRALL SA (ES) | 2021-02-03 | — | — | EP | disclosed |
| US-20200197348-A1 | Pharmaceutical Compositions Comprising Dimethyl Fumarate | ALMIRALL, S.A. (ES) | 2020-06-25 | — | — | US | disclosed |
| EP-1592680-B9 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2009-03-25 | — | — | EP | disclosed |
| EP-1592680-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2008-05-07 | — | — | EP | disclosed |
| EP-1592680-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL LAB (ES) | 2008-05-07 | — | — | EP | disclosed |
| US-20060142380-A1 | 2-Phenylpyran-4-one derivatives as selective cox-2 inhibitors | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-29 | — | — | US | disclosed |
| EP-1592680-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | Almirall Prodesfarma, S.A. (ES) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072058-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142380-A1 | 2-Phenylpyran-4-one derivatives as selective cox-2 inhibitors | PTGS2, PTGES2, PTGS1 | PTGS2 1/4885PTGS1 3/4885 |
| US-11602515-B2 | Pharmaceutical compositions comprising dimethyl fumarate | MGAM, SI, FH | PTGS2 2276/4885PTGS1 1521/4885 |
| US-20210330628-A1 | Pharmaceutical Compositions Comprising Dimethyl Fumarate | MGAM, SI, FH | PTGS2 2168/4885PTGS1 1359/4885 |
| US-20200197348-A1 | Pharmaceutical Compositions Comprising Dimethyl Fumarate | MGAM, SI, FH | PTGS2 2276/4885PTGS1 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.