SCHEMBL3908879

SCHEMBL3908879

COC(C)OC(C)O[Si](COC(=O)Cc1ccncc1)(OC(C)OC(C)OC)OC(C)OC(C)OC

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 19/20 0.53
TSHR P16473 1/20 0.34
CYP17A1 P05093 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914289 0.87 CYP19A1 (0.58) CYP19A1CYP17A1
SCHEMBL3916939 0.85 CYP19A1 (0.55) CYP19A1TSHR
SCHEMBL3910175 0.81 ADRB2 (0.42) TSHR
SCHEMBL3908792 0.80 CYP19A1 (0.56) CYP19A1CYP17A1
SCHEMBL3912380 0.79 CYP1A2 (0.40) TSHR
SCHEMBL5315543 0.75 CYP19A1 (0.49) CYP19A1TSHRCYP17A1
SCHEMBL3913250 0.75 CYP19A1 (0.54) CYP19A1CYP17A1
SCHEMBL3908545 0.73 CYP19A1 (0.55) CYP19A1CYP17A1
SCHEMBL3908793 0.71 KMT2A (0.41) TSHR
SCHEMBL3908881 0.71 CYP19A1 (0.50) CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed