Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910730 | 0.88 | CYP1A2 (0.38) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL3909266 | 0.86 | HPGD (0.38) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL4349768 | 0.80 | PKM (0.47) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL3908879 | 0.79 | CYP19A1 (0.53) | TSHR | |
| SCHEMBL3917973 | 0.77 | LMNA (0.46) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL5312198 | 0.77 | CYP1A2 (0.43) | CYP1A2PGRADORA3PTGS1SLC6A2 | |
| SCHEMBL3909806 | 0.75 | ALDH1A1 (0.43) | CYP1A2ALDH1A1TSHRPPARGPPARA | |
| SCHEMBL3912383 | 0.73 | MEN1 (0.38) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL30858931 | 0.72 | LMNA (0.56) | CYP1A2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL134991 | 0.72 | LMNA (0.56) | CYP1A2ALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090277559-A1 | METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1840158-B1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2009-02-18 | — | — | EP | disclosed |